Description

3-Pyridinecarbonyl Chloride, 6-Cyano-, 1-Oxide (9Ci) is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its unique structure, featuring a reactive acid chloride group, a cyano substituent, and an N-oxide moiety, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Utilized to create labeled compounds and activity-based probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 6-Cyano-, 1-Oxide (9Ci)
CAS No.	760949-71-1
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	6-Cyanonicotinoyl Chloride N-Oxide; 6-Cyanopyridine-3-carbonyl Chloride 1-Oxide; 3-Cyano-6-pyridinecarbonyl Chloride N-Oxide; 6-Cyano-3-pyridinecarboxylic Acid Chloride N-Oxide; 6-Cyanonicotinic Acid Chloride N-Oxide; 6-Cyano-3-pyridoyl Chloride 1-Oxide; 760949-71-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 6-Cyano-, 1-Oxide (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.