Description

Benzoyl Chloride, 4-(2-Methoxyethoxy)- (9Ci) is a specialized benzoyl chloride derivative featuring a hydrophilic 2-methoxyethoxy substituent at the para position. This functionalization makes it a valuable key synthetic intermediate for introducing a polar, ether-linked side chain into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex organic architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates requiring solubility-enhancing moieties.
• Polymer Chemistry: Used as a monomer or functionalization agent in the production of specialty polymers, such as polyesters or polyamides with tailored ether side chains.
• Liquid Crystal & OLED Materials: Acts as a precursor for synthesizing advanced organic electronic materials where the 2-methoxyethoxy group influences mesomorphic or charge-transport properties.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides or fungicides, where its structure can contribute to biological activity and environmental profile.
• Dye & Pigment Manufacturing: Functions as an intermediate for creating specialized dyes and pigments with modified solubility and application characteristics.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Heck) as an electrophilic coupling partner to introduce the benzoyl-protected phenolic ether group.
• Surface Modification Agent: Can be used to functionalize surfaces or nanoparticles, imparting specific chemical reactivity or compatibility through the benzoyl chloride group.

Basic Information

Product Name	Benzoyl Chloride, 4-(2-Methoxyethoxy)- (9Ci)
CAS No.	756478-87-2
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	4-(2-Methoxyethoxy)benzoyl chloride; 2-Methoxyethyl 4-(chlorocarbonyl)phenyl ether; p-(2-Methoxyethoxy)benzoyl chloride; 4-(2-Methoxyethoxy)benzoic acid chloride; Benzoyl chloride, 4-(2-methoxyethoxy)-; [4-(2-Methoxyethoxy)phenyl]carbonyl chloride
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 4-(2-Methoxyethoxy)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Isolate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.