Description

2H-Thiopyran-3-Carbonyl Chloride, 3-Aminotetrahydro- (9Ci) is a specialized heterocyclic building block featuring both an amine and a highly reactive acid chloride functional group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique thiopyran scaffold for biological activity.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying biological pathways and protein interactions due to its reactive handles for conjugation.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	2H-Thiopyran-3-Carbonyl Chloride, 3-Aminotetrahydro- (9Ci)
CAS No.	754916-86-4
Molecular Formula	C6H8ClNOS
Molecular Weight	177.65 g/mol
Synonyms	3-Aminotetrahydro-2H-thiopyran-3-carbonyl chloride; 3-Amino-3,4,5,6-tetrahydro-2H-thiopyran-3-carbonyl chloride; Tetrahydro-3-amino-2H-thiopyran-3-carbonyl chloride; 3-Aminoperhydro-2H-thiopyran-3-carbonyl chloride; 2H-Thiopyran-3-carbonyl chloride, 3-amino-tetrahydro-; 754916-86-4; 3-Amino-3,4,5,6-tetrahydro-2H-thiopyran-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2H-Thiopyran-3-Carbonyl Chloride, 3-Aminotetrahydro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.