Description

5-Methylthiophene-3-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound serves as a critical building block for introducing the 5-methylthiophene-3-carbonyl moiety into target molecules, enabling the development of novel compounds with specific functionalities. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Building block for creating functional polymers, liquid crystals, and organic electronic materials due to its conjugated thiophene structure.
• Chemical Biology Probes: Employed in the development of molecular probes and labeling reagents for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic acid chlorides.

Basic Information

Product Name	5-Methylthiophene-3-Carbonyl Chloride
CAS No.	754190-97-1
Molecular Formula	C7H7ClOS
Molecular Weight	174.65 g/mol
Synonyms	3-(Chlorocarbonyl)-5-methylthiophene; 5-Methyl-3-thiophenecarbonyl chloride; 5-Methylthiophene-3-carboxylic acid chloride; 3-Carboxy-5-methylthiophene chloride; 5-Methyl-3-thienoyl chloride; 5-Methyl-3-thiophenecarboxylic acid chloride; 5-Methylthiophene-3-carbonyl chloride; 3-Thiophenecarbonyl chloride, 5-methyl-
EINECS	Contact for details

Quality Control

Our 5-Methylthiophene-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider refrigeration (2-8°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.