Description

m-Peg4-Phosphonic Acid is a specialized bifunctional linker molecule featuring a methoxy-terminated tetraethylene glycol (PEG) spacer and a phosphonic acid group. This unique structure is critical for creating stable, hydrophilic conjugates and surface modifications, bridging organic and inorganic materials. It is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors who require precise molecular tethering and functionalization capabilities.

Application

• Bioconjugation reagent for attaching biomolecules (peptides, proteins, oligonucleotides) to surfaces or other molecules.
• Surface modification agent for metal oxides (e.g., titanium dioxide, iron oxide) to impart hydrophilicity and biofunctionality.
• Key intermediate in the synthesis of targeted drug delivery systems and antibody-drug conjugates (ADCs).
• Building block for functionalized polymers and hydrogels with enhanced biocompatibility.
• Anchor group for creating self-assembled monolayers (SAMs) on metal and metal oxide substrates for sensor development.
• Linker in the preparation of diagnostic assays and imaging probes.

Basic Information

Product Name	m-Peg4-Phosphonic Acid
CAS No.	750541-89-0
Molecular Formula	C11H25O8P
Molecular Weight	316.29 g/mol
Synonyms	2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethylphosphonic Acid; (2-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phosphonic Acid; mPEG4-phosphonic acid; Methoxy-PEG4-phosphonic Acid; 4-Arm-PEG-Phosphonate; O-(2-Methoxyethyl)-O'-(2-phosphonoethyl)undecaethylene glycol; Phosphonic acid P-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl] ester
EINECS	Contact for details

Quality Control

Our m-Peg4-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.