Description

1H-Imidazole-4-Carbonyl Chloride, 2-Propyl- (9Ci) is a specialized, high-purity organic intermediate featuring a reactive carbonyl chloride group on an imidazole ring. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key building block. It is primarily sought by fine chemical manufacturers and R&D laboratories in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and advanced organic materials.
• Bioconjugation & Probe Development: The reactive acid chloride group enables coupling reactions for creating biochemical probes, diagnostic agents, and labeled compounds.
• Academic & Industrial R&D: Serves as a versatile reagent in organic chemistry research for constructing complex heterocyclic systems and exploring new synthetic methodologies.

Basic Information

Product Name	1H-Imidazole-4-Carbonyl Chloride, 2-Propyl- (9Ci)
CAS No.	749192-75-4
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	2-Propyl-1H-imidazole-4-carbonyl chloride; 2-Propyl-1H-imidazole-4-carboxylic acid chloride; 2-Propylimidazole-4-carbonyl chloride; 1H-Imidazole-4-carbonyl chloride, 2-propyl-; 749192-75-4; 2-n-Propyl-1H-imidazole-4-carbonyl chloride; 2-Propyl-1H-imidazole-4-carboxyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-4-Carbonyl Chloride, 2-Propyl- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.