Description

(R)-(+)-1-Phenylpropyl Isothiocyanate CAS NO 745784-00-3 is a high-purity chiral isothiocyanate derivative, a critical building block in asymmetric synthesis and pharmaceutical research. Its enantiomeric purity makes it an essential reagent for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel, targeted pesticides and herbicides with specific chiral activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Flavor and Fragrance Industry: Intermediate for the synthesis of complex, high-value chiral aroma compounds.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-(+)-1-Phenylpropyl Isothiocyanate
CAS No.	745784-00-3
Molecular Formula	C10H11NS
Molecular Weight	177.26 g/mol
Synonyms	(R)-1-Phenylpropyl isothiocyanate; (R)-(+)-1-Phenyl-1-propyl isothiocyanate; (R)-α-Ethylbenzyl isothiocyanate; (R)-1-Phenylpropyl mustard oil; (R)-sec-Butylbenzene isothiocyanate; (R)-1-Isothiocyanato-1-phenylpropane; (R)-Phenylpropyl isothiocyanate; (R)-1-Phenylpropylisothiocyanate
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Phenylpropyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.