Description

(1R,2R)-(-)-2-Benzyloxycyclohexyl Isothiocyanate is a chiral, non-racemic organic compound featuring both an isothiocyanate functional group and a benzyl-protected alcohol moiety. This specific stereochemistry makes it a valuable chiral building block and derivatization agent in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of enantiomerically pure compounds, including potential drug candidates and bioactive molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a key precursor for the development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used in the synthesis of novel, stereospecific pesticides and herbicides.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Derivatization Agent for Chiral Analysis: Employed to create diastereomeric derivatives for the analysis and separation of enantiomers via techniques like HPLC or GC.
• Material Science Research: Investigated for the preparation of chiral monomers or functional materials with specific optical properties.
• Academic & Industrial R&D: A critical reagent for methodological studies in stereoselective synthesis and reaction development.

Basic Information

Product Name	(1R,2R)-(-)-2-Benzyloxycyclohexyl Isothiocyanate
CAS No.	745783-98-6
Molecular Formula	C14H17NOS
Molecular Weight	247.35 g/mol
Synonyms	(1R,2R)-2-(Benzyloxy)cyclohexyl isothiocyanate; (-)-trans-2-Benzyloxycyclohexyl isothiocyanate; (1R,2R)-(-)-2-(Phenylmethoxy)cyclohexyl isothiocyanate; trans-2-Benzyloxycyclohexyl isothiocyanate; (1R,2R)-2-Benzyloxycyclohexyl mustard oil; Cyclohexanol, 2-(benzyloxy)-, 1-isothiocyanate, (1R,2R)-
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-2-Benzyloxycyclohexyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, enantiomeric excess (ee), and identity. Certificates of Analysis (COA) detailing specific results for chiral purity (HPLC), assay, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.