Description

Chidamide is a novel, potent, and selective histone deacetylase (HDAC) inhibitor, specifically targeting Class I and IIb HDACs. This mechanism of action makes it a critical compound for epigenetic research and the development of targeted cancer therapies. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on oncology and epigenetics.

Application

• Pharmaceutical Research & Development: As a key active pharmaceutical ingredient (API) in the development of novel anti-cancer therapeutics.
• Preclinical & Clinical Studies: For investigating the efficacy and pharmacokinetics of HDAC inhibition in various cancer models.
• Biochemical Research: Used as a selective tool compound to study epigenetic regulation, gene expression, and chromatin remodeling in cellular pathways.
• Oncology Drug Discovery: Serves as a reference standard and a lead compound for synthesizing new derivatives with improved pharmacological profiles.
• Academic Research: Employed in university and institutional labs for fundamental studies in cancer biology and epigenetics.

Basic Information

Product Name	Chidamide
CAS No.	743420-02-2
Molecular Formula	C22H19FN4O2
Molecular Weight	390.41 g/mol
Synonyms	Epidaza; HBI-8000; Tucidinostat; CS-055; N-(2-Amino-4-fluorophenyl)-4-[[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]amino]benzamide; Chidamid; Chidamidum
EINECS	Contact for details

Quality Control

Our Chidamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring compliance with research-grade specifications and supporting your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.