Description

6-Benzothiazolecarbonyl Chloride, 2-Amino- (9Ci) CAS NO 743384-25-0 is a specialized benzothiazole derivative, specifically an amino-substituted acid chloride, that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites—the acid chloride group and the amino group—enabling its use in the construction of complex heterocyclic systems and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel benzothiazole-based drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of new fungicides, herbicides, and insecticides that leverage the benzothiazole scaffold for enhanced biological activity.
• Material Science Research: Serves as a precursor for creating functional polymers, dyes, and fluorescent markers due to its reactive functional groups.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and protein interactions.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Peptide Mimetics: Utilized to incorporate the benzothiazole moiety into peptide chains, creating analogs with modified stability or receptor binding profiles.

Basic Information

Product Name	6-Benzothiazolecarbonyl Chloride, 2-Amino- (9Ci)
CAS No.	743384-25-0
Molecular Formula	C8H5ClN2OS
Molecular Weight	212.65 g/mol
Synonyms	2-Amino-6-benzothiazolecarbonyl chloride; 2-Aminobenzo[d]thiazole-6-carbonyl chloride; 6-(Chlorocarbonyl)-2-aminobenzothiazole; 2-Amino-1,3-benzothiazole-6-carbonyl chloride; 2-Aminobenzothiazole-6-carboxylic acid chloride; 2-Amino-6-(chlorocarbonyl)benzothiazole; 6-Carboxy-2-aminobenzothiazole chloride
EINECS	Contact for details

Quality Control

Our 6-Benzothiazolecarbonyl Chloride, 2-Amino- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.