Description

1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol is a high-value fluorinated aromatic alcohol building block. This compound is critical for introducing the highly lipophilic and electron-withdrawing bis(trifluoromethyl)phenyl group into target molecules, significantly altering their physicochemical properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of advanced active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethyl groups enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated moiety contributes to improved efficacy, photostability, and rainfastness.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials to modify solubility, dielectric properties, and thermal stability.
• Chemical Biology Probe: Useful for creating molecular probes and tags to study biological processes and protein-ligand interactions due to its distinct spectroscopic signature.

Basic Information

Product Name	1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol
CAS No.	742097-70-7
Molecular Formula	C₁₁H₈F₆O
Molecular Weight	270.17 g/mol
Synonyms	3,5-Bis(trifluoromethyl)benzenepropanol; 1-[3,5-Bis(trifluoromethyl)phenyl]-1-propanol; 3,5-Bis(trifluoromethyl)phenylpropyl alcohol; α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol; 3,5-Bis(trifluoromethyl)benzene-1-propanol; 3,5-Bis(trifluoromethyl)phenethyl carbinol; (3,5-Bis(trifluoromethyl)phenyl)propanol
EINECS	Contact for details

Quality Control

Our 1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.