Description

Quinoline, 4-Isothiocyanato-2-Methyl- (9Ci) CAS NO 742060-73-7 is a specialized heterocyclic organic compound featuring a reactive isothiocyanate functional group attached to a methyl-substituted quinoline core. This unique structure makes it a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the development of targeted therapies and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel quinoline-based drug candidates, including potential anticancer, antimicrobial, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the isothiocyanate moiety can be leveraged for bioactivity.
• Chemical Biology Probe: Acts as a reactive handle in bioconjugation chemistry for labeling proteins, peptides, or other biomolecules due to the isothiocyanate group's affinity for amines.
• Material Science Research: Investigated as a precursor for functionalized polymers or metal-organic frameworks (MOFs) with specialized optical or catalytic properties.
• Dye and Pigment Synthesis: Utilized in the creation of advanced colorants and fluorescent markers based on the quinoline scaffold.

Basic Information

Item	Detail
Product Name	Quinoline, 4-Isothiocyanato-2-Methyl- (9Ci)
CAS No.	742060-73-7
Molecular Formula	C11H8N2S
Molecular Weight	200.26 g/mol
Synonyms	4-Isothiocyanato-2-methylquinoline; 2-Methyl-4-isothiocyanatoquinoline; 4-Isothiocyanato-2-methylquinoline (9CI); 2-Methylquinolin-4-yl isothiocyanate; 4-Isothiocyanato-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Every batch of Quinoline, 4-Isothiocyanato-2-Methyl- (9Ci) is produced and tested under strict quality management protocols. We guarantee high purity and batch-to-batch consistency through comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.