Description

2-Piperidinecarbonyl Chloride, (S)- (9Ci) is a high-value, chiral building block and an activated carboxylic acid derivative. This compound is critical for the synthesis of enantiomerically pure pharmaceuticals and advanced organic molecules, where stereochemical control is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Peptide Mimetics & Protease Inhibitor Synthesis: Used in the construction of peptide backbones and inhibitors that mimic natural substrates.
• Asymmetric Synthesis: Serves as a precursor for introducing the (S)-pipecolic acid moiety or other chiral piperidine derivatives into complex molecular architectures.
• Agrochemical Research: Employed in the development of chiral herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Useful for synthesizing chiral ligands for asymmetric catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services targeting specific client projects.

Basic Information

Product Name	2-Piperidinecarbonyl Chloride, (S)- (9Ci)
CAS No.	741633-48-7
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	(S)-Piperidine-2-carbonyl chloride; (S)-2-Piperidinecarbonyl chloride; L-Pipecolyl chloride; (S)-Pipecolyl chloride; (2S)-Piperidine-2-carbonyl chloride; (S)-2-(Chlorocarbonyl)piperidine; 741633-48-7; (S)-1-(2-Piperidyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarbonyl Chloride, (S)- is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; handle and store accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.