Description

6-Bromonicotinoyl Chloride is a versatile and reactive halogenated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, where the acid chloride group enables efficient amide or ester formation, and the bromine atom provides a handle for further cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides with specific activity profiles.
• Ligand and Catalyst Development: Building block for creating specialized ligands used in catalytic systems and material science.
• Chemical Research & Development: A versatile reagent for constructing complex pyridine-based heterocycles in academic and industrial R&D settings.
• Material Science: Intermediate for the synthesis of functionalized polymers and organic electronic materials.

Basic Information

Product Name	6-Bromonicotinoyl Chloride
CAS No.	740841-42-3
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Bromonicotinic Acid Chloride; 6-Bromopyridine-3-carbonyl Chloride; 3-Bromo-5-pyridinecarbonyl Chloride; 6-Bromonicotinyl Chloride; 6-Bromo-3-pyridinecarbonyl Chloride; 6-Bromonicotinic Acid Chloride; 6-Bromo-3-pyridinecarboxylic Acid Chloride; 6-Bromonicotinoyl Chloride CAS 740841-42-3
EINECS	Contact for details

Quality Control

Our 6-Bromonicotinoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.