Description

2-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, (1S,3R,4R)- (9Ci) is a highly functionalized, chiral bicyclic building block of significant interest in advanced organic synthesis. Its value lies in its rigid, three-dimensional scaffold and reactive acid chloride group, which enable the efficient construction of complex, stereodefined molecular architectures. This compound is essential for research chemists and process development teams in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including potential treatments for neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts.
• Peptidomimetics & Constrained Peptide Synthesis: The bicyclic structure is ideal for introducing conformational constraints into peptide backbones to improve stability and biological activity.
• Material Science: Potential monomer for creating specialized polymers with unique structural and chiral properties.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Item	Details
Product Name	2-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, (1S,3R,4R)- (9Ci)
CAS No.	738567-65-2
Molecular Formula	C7H10ClNO
Molecular Weight	159.61 g/mol
Synonyms	(1S,3R,4R)-Bicyclo[2.2.1]heptane-2-carboxylic acid chloride, 2-aza-; (1S,3R,4R)-2-Azabicyclo[2.2.1]heptane-3-carbonyl chloride; endo-(1S,4R)-3-(Chlorocarbonyl)-2-azabicyclo[2.2.1]heptane; (1S,3R,4R)-3-(Chlorocarbonyl)-2-azabicyclo[2.2.1]heptane; 2-Azanorbornane-3-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our production of 2-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, (1S,3R,4R)- (9Ci) adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized by advanced analytical techniques to ensure identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing specific results for chiral purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.