Description

(S)-(-)-1-Phenylpropyl Isothiocyanate is a high-purity chiral isothiocyanate building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of pharmaceuticals and bioactive molecules, particularly where stereochemistry is critical for biological activity. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, especially those targeting specific enantioselective pathways.
• Agrochemical Research: Used in the development of novel, stereochemically-defined pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalysis.
• Bioconjugation Chemistry: The reactive isothiocyanate group enables conjugation with amines, useful in probe and linker molecule synthesis.
• Natural Product Analog Synthesis: Employed in the synthetic modification of natural product scaffolds to explore new bioactive compounds.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialized polymeric materials.

Basic Information

Product Name	(S)-(-)-1-Phenylpropyl Isothiocyanate
CAS No.	737001-04-6
Molecular Formula	C10H11NS
Molecular Weight	177.26 g/mol
Synonyms	(S)-1-Phenylpropyl isothiocyanate; (S)-(-)-1-Phenylpropyl isothiocyanate; (S)-α-Methylphenethyl isothiocyanate; (S)-1-Phenyl-1-propyl isothiocyanate; (S)-1-Phenylpropyl mustard oil; (S)-sec-Butylbenzene isothiocyanate; (S)-Phenylpropyl isothiocyanate; (1S)-1-Phenylpropyl isothiocyanate
EINECS	Contact for details

Quality Control

Our (S)-(-)-1-Phenylpropyl Isothiocyanate is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical characterization, including chiral HPLC, to verify identity, purity, and optical rotation. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is sensitive to strong alkali and should be kept away from such conditions. For long-term storage, consider inert atmosphere handling to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.