Description

(R)-(-)-3-Methyl-2-Butyl Isothiocyanate is a high-purity chiral isothiocyanate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals, agrochemicals, and specialty materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require optically active intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides, herbicides, and fungicides to enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Bioconjugation and Probe Synthesis: Useful in biochemical research for labeling proteins and other biomolecules via its reactive isothiocyanate group.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with unique chiral properties.

Basic Information

Item	Detail
Product Name	(R)-(-)-3-Methyl-2-Butyl Isothiocyanate
CAS No.	737001-02-4
Molecular Formula	C6H11NS
Molecular Weight	129.22 g/mol
Synonyms	(R)-3-Methyl-2-butyl isothiocyanate; (R)-(-)-3-Methyl-2-butyl isothiocyanate; (2R)-3-Methylbutan-2-yl isothiocyanate; (R)-Sec-butyl isothiocyanate; (R)-1,2-Dimethylpropyl isothiocyanate; (R)-1-Methyl-1-ethylpropyl isothiocyanate; (R)-Isothiocyanato-3-methyl-2-butane
EINECS	Contact for details

Quality Control

Our (R)-(-)-3-Methyl-2-Butyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and highly volatile; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.