Description

(R)-(-)-1-Indanyl Isothiocyanate CAS NO 737000-97-4 is a high-purity chiral building block characterized by its isothiocyanate functional group attached to an indane scaffold. This compound matters as a critical intermediate for the synthesis of novel pharmaceuticals and agrochemicals, where its stereochemistry and reactive moiety enable the creation of targeted, high-value molecules. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries for applications in medicinal chemistry, asymmetric synthesis, and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel, stereospecific pesticides and herbicides with enhanced activity and selectivity.
• Chemical Biology Probe: Serves as a reactive handle for bioconjugation and labeling of proteins or other biomolecules to study biological pathways.
• Asymmetric Catalyst Ligand Synthesis: Building block for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science: Intermediate in the synthesis of specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	(R)-(-)-1-Indanyl Isothiocyanate
CAS No.	737000-97-4
Molecular Formula	C10H9NS
Molecular Weight	175.25 g/mol
Synonyms	(1R)-1,2-Dihydro-1H-inden-1-yl isothiocyanate; (R)-1-Indanyl isothiocyanate; (-)-1-Indanyl isothiocyanate; (R)-(-)-1,2-Dihydro-1H-inden-1-yl isothiocyanate; (R)-1,2-Dihydro-1H-inden-1-yl isothiocyanate; NSC 405124; (R)-Indane-1-isothiocyanate
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Indanyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C for long-term stability. Due to its highly volatile nature, allow the container to reach room temperature before opening to minimize loss and prevent condensation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.