Description

(1S,2S)-(+)-2-Benzyloxycyclopentyl Isothiocyanate is a high-purity chiral building block and key intermediate in advanced organic synthesis. Its defined stereochemistry and reactive isothiocyanate functional group make it a critical reagent for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the design and production of advanced, stereospecific pesticides and herbicides.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating isothiocyanate-based probes to study protein function and biomolecular interactions.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Material Science: Potential monomer or cross-linking agent for synthesizing specialized polymers with unique optical or mechanical properties.

Basic Information

Product Name	(1S,2S)-(+)-2-Benzyloxycyclopentyl Isothiocyanate
CAS No.	737000-91-8
Molecular Formula	C13H15NOS
Molecular Weight	233.33 g/mol
Synonyms	(1S,2S)-2-(Benzyloxy)cyclopentyl isothiocyanate; (+)-(1S,2S)-2-Benzyloxycyclopentyl isothiocyanate; (1S,2S)-rel-2-(Phenylmethoxy)cyclopentyl isothiocyanate; NSC 758463; 2-Benzyloxycyclopentyl isothiocyanate, (1S,2S)-(+)-; Cyclopentanol, 2-(phenylmethoxy)-, 1-isothiocyanate, (1S,2S)-
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Benzyloxycyclopentyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.