Description

(1R,2R)-(-)-2-Benzyloxycyclopentyl Isothiocyanate is a chiral, non-racemic organic compound featuring both an isothiocyanate and a benzyl-protected alcohol functional group. This specific stereochemistry makes it a valuable chiral building block and derivatization agent in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of enantiomerically pure molecules, including potential drug candidates and bioactive compounds.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for constructing enantiomerically pure heterocycles and complex molecular scaffolds with defined stereocenters.
• Agrochemical Research & Development: Used in the synthesis of novel, stereospecific pesticides and herbicides where biological activity is chirality-dependent.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Derivatization Agent for Chiral Analysis: Can be used to derivative chiral amines or alcohols for analysis via chromatographic techniques (e.g., HPLC, GC) to determine enantiomeric purity.
• Academic and Industrial Research: Employed in methodological studies and the discovery of new chemical entities in synthetic organic chemistry laboratories.

Basic Information

Product Name	(1R,2R)-(-)-2-Benzyloxycyclopentyl Isothiocyanate
CAS No.	737000-90-7
Molecular Formula	C13H15NO2S
Molecular Weight	249.33 g/mol
Synonyms	(1R,2R)-2-(Benzyloxy)cyclopentyl isothiocyanate; (-)-trans-2-Benzyloxycyclopentyl isothiocyanate; (1R,2R)-(-)-2-(Benzyloxy)cyclopentyl isothiocyanate; trans-2-Benzyloxycyclopentyl isothiocyanate; (1R,2R)-2-Benzyloxy-1-cyclopentyl isothiocyanate; Benzyl (1R,2R)-2-isothiocyanatocyclopentyl ether; Cyclopentanol, 2-isothiocyanato-, 2-(phenylmethyl) ether, (1R,2R)-(-)-
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-2-Benzyloxycyclopentyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC, Chiral GC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.