Description

(1S,2S)-(+)-2-Benzyloxycyclohexyl Isothiocyanate is a chiral, non-racemic organic compound belonging to the isothiocyanate class, characterized by its specific stereochemistry at the cyclohexyl ring. This compound serves as a versatile and high-value chiral building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides where specific chirality is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to develop isothiocyanate-based probes for protein labeling and activity-based profiling studies due to its reactive -NCS group.
• Material Science: Potential monomer or cross-linking agent for the synthesis of specialty polymers with unique optical or mechanical properties.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(1S,2S)-(+)-2-Benzyloxycyclohexyl Isothiocyanate
CAS No.	737000-89-4
Molecular Formula	C14H17NOS
Molecular Weight	247.35 g/mol
Synonyms	(1S,2S)-2-(Benzyloxy)cyclohexyl isothiocyanate; (+)-(1S,2S)-2-Benzyloxycyclohexyl isothiocyanate; trans-2-Benzyloxycyclohexyl isothiocyanate; (1S,2S)-rel-2-(Phenylmethoxy)cyclohexyl isothiocyanate; 2-Benzyloxycyclohexyl isothiocyanate, (1S,2S)-(+)-; Cyclohexanol, 2-(phenylmethoxy)-, 1-isothiocyanate, (1S,2S)-
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Benzyloxycyclohexyl Isothiocyanate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and custom purity grades or analytical data packages can be provided to meet specific research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.