Description

(S)-(+)-1-(4-Fluorophenyl)Ethyl Isothiocyanate is a high-purity chiral building block and key synthetic intermediate. This compound matters for its role in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate a fluorinated, chiral phenethyl isothiocyanate moiety into their target compounds.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of potential drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel, optically active pesticides and herbicides with enhanced biological activity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function.
• Material Science: A monomer or cross-linking agent in the research of specialty polymers with specific optical or electronic properties.
• Reference Standard: Used as an analytical standard for quality control and method development in chiral separation techniques.

Basic Information

Product Name	(S)-(+)-1-(4-Fluorophenyl)Ethyl Isothiocyanate
CAS No.	737000-83-8
Molecular Formula	C9H8FNS
Molecular Weight	181.23 g/mol
Synonyms	(S)-1-(4-Fluorophenyl)ethyl isothiocyanate; (S)-(+)-α-Methyl-4-fluorobenzyl isothiocyanate; (S)-1-(4-Fluorophenyl)ethanamine, NCS derivative; (S)-(-)-1-(4-Fluorophenyl)ethyl isothiocyanate (enantiomer); p-Fluoro-(S)-phenethyl isothiocyanate; (S)-4-Fluoro-α-methylbenzyl isothiocyanate; (S)-1-(4-Fluorophenyl)ethyl mustard oil
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-(4-Fluorophenyl)Ethyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Due to its sensitivity, allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.