Description

(S)-(+)-1-(4-Chlorophenyl)Ethyl Isothiocyanate is a high-purity chiral building block and key synthetic intermediate. This compound is valued for its role in the stereoselective synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the preparation of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of isothiocyanate-containing probes for studying protein function and cellular processes.
• Material Science Research: A building block for novel chiral polymers and liquid crystals with specific optical properties.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring high enantiomeric purity.

Basic Information

Product Name	(S)-(+)-1-(4-Chlorophenyl)Ethyl Isothiocyanate
CAS No.	737000-81-6
Molecular Formula	C9H8ClNS
Molecular Weight	197.68 g/mol
Synonyms	(S)-1-(4-Chlorophenyl)ethyl isothiocyanate; (S)-(+)-1-(p-Chlorophenyl)ethyl isothiocyanate; (S)-α-(4-Chlorophenyl)ethyl isothiocyanate; (S)-PEITC; (S)-1-(4-Chlorophenyl)ethyl mustard oil; (S)-4-Chloro-α-methylbenzyl isothiocyanate; (S)-(+)-1-(4'-Chlorophenyl)ethyl isothiocyanate
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-(4-Chlorophenyl)Ethyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity (assay), chiral purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.