Description

(R)-(-)-1-(4-Chlorophenyl)Ethyl Isothiocyanate is a high-purity chiral building block and key synthetic intermediate. This compound matters for its role in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of novel, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Material Science Research: Intermediate for synthesizing specialized monomers or additives with specific stereochemical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(R)-(-)-1-(4-Chlorophenyl)Ethyl Isothiocyanate
CAS No.	737000-80-5
Molecular Formula	C9H8ClNS
Molecular Weight	197.68 g/mol
Synonyms	(R)-1-(4-Chlorophenyl)ethyl isothiocyanate; (R)-(-)-1-(p-Chlorophenyl)ethyl isothiocyanate; (R)-α-(4-Chlorophenyl)ethyl isothiocyanate; (R)-1-(4-Chlorophenyl)ethan-1-yl isothiocyanate; (R)-PEITC; (R)-CITC; (R)-(-)-1-(4-Chlorophenyl)ethyl mustard oil
EINECS	Contact for details

Quality Control

Every batch of (R)-(-)-1-(4-Chlorophenyl)Ethyl Isothiocyanate is produced and tested under strict quality management protocols to ensure identity, purity, and enantiomeric excess meet the high standards required for advanced synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed chromatographic and spectroscopic data, including chiral purity, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.