Description

1H-Pyrrole-2-Carbonyl Chloride, 3-Chloro- (9Ci) is a highly reactive and versatile chemical building block, specifically a functionalized pyrrole derivative. Its core value proposition lies in its role as a key acylating agent for the synthesis of complex heterocyclic compounds and advanced pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require precise molecular scaffolds. Its reactive carbonyl chloride group enables efficient derivatization, making it a critical reagent for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrole or indole core structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage heterocyclic chemistry for enhanced bioactivity.
• Material Science Research: Acts as a monomer or building block for creating advanced polymers, conductive materials, and organic electronic components.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Dye & Pigment Manufacturing: Utilized in the production of specialized heterocyclic dyes and organic pigments.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	1H-Pyrrole-2-Carbonyl Chloride, 3-Chloro- (9Ci)
CAS No.	721450-11-9
Molecular Formula	C5H3Cl2NO
Molecular Weight	163.99 g/mol
Synonyms	3-Chloro-1H-pyrrole-2-carbonyl chloride; 3-Chloropyrrole-2-carbonyl chloride; 3-Chloro-2-pyrrolylcarbonyl chloride; 3-Chloro-1H-pyrrole-2-carboxylic acid chloride; 2-Carbonyl chloride-3-chloropyrrole; 3-Chloro-pyrrole-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonyl Chloride, 3-Chloro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by techniques including HPLC, GC, NMR, and IR spectroscopy. We are committed to meeting the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Containers must be kept tightly sealed when not in use to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.