Description

6-Quinolinecarbonyl Chloride, 4-Hydroxy- (9Ci) is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a reactive acyl chloride intermediate, enabling the efficient introduction of the 4-hydroxyquinoline-6-carbonyl moiety into complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of potential drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalizing agent for specialty polymers, ligands, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags, affinity labels, and other molecular probes for biological research.
• Catalyst Ligand Development: Useful for constructing novel chelating ligands in asymmetric catalysis and coordination chemistry.

Basic Information

Product Name	6-Quinolinecarbonyl Chloride, 4-Hydroxy- (9Ci)
CAS No.	717871-71-1
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	4-Hydroxyquinoline-6-carbonyl chloride; 4-Hydroxy-6-quinolinecarboxylic acid chloride; 6-(Chlorocarbonyl)-4-hydroxyquinoline; 4-Hydroxyquinoline-6-carboxylic acid chloride; 4-Hydroxy-6-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Quinolinecarbonyl Chloride, 4-Hydroxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and acid-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.