Description

2'-C-Methyl Isoguanosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the discovery of nucleoside-based drugs targeting RNA viruses and specific cellular pathways. The high-purity material is essential for ensuring the efficacy and safety of downstream pharmaceutical products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Discovery: Used in the development of therapeutics targeting hepatitis C virus (HCV) and other RNA viruses.
• Biochemical Research: Serves as a tool compound for studying enzyme inhibition, particularly polymerases and kinases involved in viral replication.
• Preclinical Studies: Employed in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) for in vitro and in vivo testing.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2'-C-Methyl Isoguanosine
CAS No.	714249-83-9
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	2'-C-Methylisoguanosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 2'-C-Me-isoguanosine; 2'-Methylisoguanosine; 2'-C-Methyl-isoG; Isoguanosine, 2'-C-methyl-; 6-Oxo-2'-C-methylpurine riboside
EINECS	Contact for details

Quality Control

Our 2'-C-Methyl Isoguanosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.