Description

1-[2,5-Anhydro-4-C-(Hydroxymethyl)-.Alpha.-L-Lyxofuranosyl]-2,4(1H,3H)-Pyrimidinedione is a specialized nucleoside analog with significant potential in advanced pharmaceutical research and development. This compound serves as a critical high-purity building block for the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery. It is essential for research institutions and pharmaceutical companies focused on developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Drug Development: Investigated for incorporation into prodrugs targeting viral polymerases, such as those from herpesviruses or hepatitis viruses.
• Labeled Compound Synthesis: Potential starting material for the synthesis of isotopically labeled (e.g., C13, N15) compounds for metabolic tracing studies.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and nucleoside science.

Basic Information

Product Name	1-[2,5-Anhydro-4-C-(Hydroxymethyl)-.Alpha.-L-Lyxofuranosyl]-2,4(1H,3H)-Pyrimidinedione
CAS No.	705967-67-5
Molecular Formula	C10H12N2O6
Molecular Weight	256.21 g/mol
Synonyms	1-(2,5-Anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl)uracil; 1-(2,5-Anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl)-2,4(1H,3H)-pyrimidinedione; Anhydrolyxofuranosyluracil; 2,5-Anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-1,4-anhydro-4-C-(hydroxymethyl)-L-lyxitol; Uracil, 1-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-
EINECS	Contact for details

Quality Control

Our 1-[2,5-Anhydro-4-C-(Hydroxymethyl)-.Alpha.-L-Lyxofuranosyl]-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.