Description

Boc-trans-Pro(4-Azido)-Oh·Dcha is a protected amino acid derivative featuring an azido functional group, primarily used as a key building block in peptide synthesis and chemical biology. This compound is essential for researchers and manufacturers requiring precise, site-specific modifications, such as click chemistry conjugation, to develop novel peptide-based therapeutics and probes. It is particularly valuable for pharmaceutical R&D, bioconjugation, and the synthesis of complex biomolecules where controlled functionalization is critical.

Application

• Peptide Synthesis: Serves as a specialized, protected proline analog for the solid-phase and solution-phase synthesis of modified peptides.
• Click Chemistry Reagent: The azido group enables efficient Huisgen 1,3-dipolar cycloaddition reactions with alkynes for bioconjugation and labeling applications.
• Pharmaceutical Intermediate: A critical building block in the research and development of peptide drugs and prodrugs.
• Chemical Biology Probes: Used to create activity-based probes and affinity tags for studying protein function and interactions.
• Material Science: Facilitates the surface functionalization of biomaterials and nanoparticles for targeted delivery systems.
• Library Synthesis: Employed in combinatorial chemistry to generate diverse arrays of azido-functionalized compounds for screening.

Basic Information

Product Name	Boc-trans-Pro(4-Azido)-Oh·Dcha
CAS No.	702679-55-8
Molecular Formula	C₁₆H₂₇N₅O₄ · C₁₄H₂₆N₂
Molecular Weight	Contact for details
Synonyms	Boc-trans-4-Azidoproline DCHA Salt; (2S,4R)-1-[(tert-Butoxy)carbonyl]-4-azidopyrrolidine-2-carboxylic Acid Dicyclohexylamine Salt; trans-4-Azido-L-proline, N-Boc-, DCHA Salt; Boc-4-Azido-L-proline Dicyclohexylammonium Salt; Boc-AzPro-OH·DCHA; N-Boc-trans-4-azidoproline DCHA salt; tert-Butyloxycarbonyl-trans-4-azido-L-proline Dicyclohexylamine Salt
EINECS	Contact for details

Quality Control

Our Boc-trans-Pro(4-Azido)-Oh·Dcha is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.