Description

4H-1,3-Benzodioxin-5-Carbonylchloride(9Ci) is a high-purity, reactive organic intermediate featuring a benzodioxin scaffold activated by an acid chloride functional group. This compound is critical for introducing the 4H-1,3-benzodioxin moiety into more complex molecular architectures via amide or ester bond formation. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting the central nervous system or possessing complex heterocyclic structures.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides that incorporate the benzodioxin ring system for enhanced biological activity.
• Material Science: Serves as a monomer or precursor for developing specialized polymers, ligands, or organic electronic materials with unique properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes, enzyme inhibitors, or labeled compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to clients in R&D.

Basic Information

Item	Details
Product Name	4H-1,3-Benzodioxin-5-Carbonylchloride(9Ci)
CAS No.	701979-12-6
Molecular Formula	C9H5ClO3
Molecular Weight	196.59 g/mol
Synonyms	5-(Chlorocarbonyl)-4H-1,3-benzodioxin; 4H-1,3-Benzodioxine-5-carbonyl chloride; 1,3-Benzodioxin-5-carbonyl chloride, 4H-; 5-Carboxy-4H-1,3-benzodioxin chloride; Benzodioxin-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4H-1,3-Benzodioxin-5-Carbonylchloride(9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.