Description

4-Chloro-3-Sulfamoylbenzoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its bifunctional nature, featuring both a sulfonamide and an acid chloride group, makes it a critical building block for creating complex, bioactive molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs), including diuretics, carbonic anhydrase inhibitors, and anti-glaucoma agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the sulfamoyl moiety for targeted biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and pigments where the chlorobenzoyl group provides stability and color fastness.
• Material Science: Building block for synthesizing functional polymers and ligands for metal-organic frameworks (MOFs) with specific adsorption properties.

Basic Information

Product Name	4-Chloro-3-Sulfamoylbenzoyl Chloride
CAS No.	700490-77-3
Molecular Formula	C7H5Cl2NO3S
Molecular Weight	254.09 g/mol
Synonyms	3-(Chlorosulfonyl)-4-chlorobenzoic acid chloride; 4-Chloro-3-sulfamoylbenzoic acid chloride; Benzoic acid, 4-chloro-3-(aminosulfonyl)-, chloride; 4-Chloro-3-sulphamoylbenzoyl chloride; 4-Chloro-3-sulfamoyl-benzoylchlorid; 700490-77-3; 4-Chloro-3-sulfamoylbenzoylchloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Sulfamoylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for sensitive synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, bases, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.