Description

1H-Imidazole-4-Carbonyl Chloride, 1-Methyl-2-Propyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key acylating agent and intermediate in the construction of complex molecular architectures, particularly those containing the imidazole pharmacophore. Pharmaceutical and agrochemical research organizations need this high-purity intermediate to develop new active ingredients, leveraging its reactive carbonyl chloride group for precise derivatization.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole ring is a key binding motif.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its structure can be incorporated into active molecules.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that require imidazole-based monomers.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or affinity tags to study biological processes.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1H-Imidazole-4-Carbonyl Chloride, 1-Methyl-2-Propyl- (9Ci)
CAS No.	700345-96-6
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	1-Methyl-2-propyl-1H-imidazole-4-carbonyl chloride; 1-Methyl-2-propylimidazole-4-carbonyl chloride; 4-(Chlorocarbonyl)-1-methyl-2-propylimidazole; 1-Methyl-2-propyl-1H-imidazole-4-carboxylic acid chloride; 700345-96-6; 1-Methyl-2-propylimidazole-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carbonyl Chloride, 1-Methyl-2-Propyl- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the stringent requirements of our global clientele in the pharmaceutical and fine chemical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.