Description

(4-Fluoronaphthalen-1-Yl)Methanol is a specialized fluorinated naphthalene derivative that serves as a versatile building block in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines the rigid naphthalene scaffold with a reactive hydroxymethyl group and a fluorine substituent, enabling precise modifications for creating complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, material science, and the development of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders or cancer therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the fluoronaphthalene moiety can enhance biological activity and environmental stability.
• Material Science & OLED Development: Serves as a building block for creating fluorinated organic semiconductors, charge-transport materials, and emissive layers in organic light-emitting diodes (OLEDs).
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized fluorinated ligands for transition metal catalysts used in cross-coupling and other fine chemical reactions.
• Fluorine Chemistry & SAR Studies: Essential for structure-activity relationship (SAR) studies in drug discovery, where the fluorine atom is used to modulate potency, metabolic stability, and membrane permeability.
• Academic & Contract Research: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	(4-Fluoronaphthalen-1-Yl)Methanol
CAS No.	79996-88-6
Molecular Formula	C11H9FO
Molecular Weight	176.19 g/mol
Synonyms	1-(Hydroxymethyl)-4-fluoronaphthalene; 4-Fluoro-1-naphthalenemethanol; (4-Fluoro-1-naphthyl)methanol; 4-Fluoronaphthalene-1-methanol; 1-Fluoro-4-(hydroxymethyl)naphthalene; 4-Fluoro-1-naphthalenylmethanol; α-Hydroxy-4-fluoronaphthalenemethane
EINECS	Contact for details

Quality Control

Our (4-Fluoronaphthalen-1-Yl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation traceability supports your R&D and scale-up processes under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.