Description

3-Chloro-5-Fluorobenzyl Alcohol is a versatile fluorinated and chlorinated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional halogenated structure makes it a valuable intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro substitution pattern can improve compound stability and efficacy.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to alter physical properties such as thermal stability, chemical resistance, and flame retardancy.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, etherification, and esterification to construct complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	3-Chloro-5-Fluorobenzyl Alcohol
CAS No.	79944-64-2
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	(3-Chloro-5-fluorophenyl)methanol; 3-Chloro-5-fluorobenzenemethanol; 1-Chloro-3-(hydroxymethyl)-5-fluorobenzene; α-Hydroxymethyl-3-chloro-5-fluorobenzene; 3-Chloro-5-fluoro benzylalcohol; 3-Cl-5-F-BnOH; 5-Fluoro-3-chlorobenzyl alcohol; 79944-64-2
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.