Description

4-Nitrophenyl-4-Morpholinophosphonochloridate is a specialized organophosphorus reagent primarily used as a key intermediate in synthetic organic chemistry. This compound matters for its role in constructing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active compounds and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with phosphate or phosphonate ester functionalities.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Peptide Chemistry: Employed as a phosphorylating or coupling agent in the synthesis of modified peptides and peptidomimetics.
• Material Science Research: Serves as a precursor for creating specialized polymers, flame retardants, or ligands for metal catalysis.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying enzyme mechanisms, particularly phosphatases and kinases.
• Process Chemistry: Acts as a reagent in scale-up and optimization processes for the commercial production of fine chemicals.

Basic Information

Product Name	4-Nitrophenyl-4-Morpholinophosphonochloridate
CAS No.	79838-05-4
Molecular Formula	C10H12ClN2O5P
Molecular Weight	306.64 g/mol
Synonyms	4-Morpholinophosphonic dichloridic acid 4-nitrophenyl ester; Phosphorochloridic acid, P-(4-morpholinyl)-, 4-nitrophenyl ester; 4-Nitrophenyl morpholinophosphonochloridate; 4-Nitrophenyl P-morpholinophosphonochloridate; Morpholin-4-yl-(4-nitrophenoxy)phosphinic chloride; 4-Nitrophenyl morpholinochlorophosphonate; 4-Nitrophenyl N-morpholinophosphonamidochloridate (common misnomer); 79838-05-4
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl-4-Morpholinophosphonochloridate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.