Description

4-Methoxyphenyl(Dimethylamino)Chlorophosphine is a specialized organophosphorus compound that serves as a versatile building block in advanced chemical synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the development of pharmaceuticals and agrochemicals. This product is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries who require high-purity, reliable intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphorus-based functional groups.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators where the phosphine moiety is integral to biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of novel organophosphorus polymers or flame retardants with tailored properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes involving phosphorylation.
• Process Chemistry: Applied in scale-up and optimization of synthetic routes for commercial production of phosphorus-containing compounds.

Basic Information

Product Name	4-Methoxyphenyl(Dimethylamino)Chlorophosphine
CAS No.	156814-16-3
Molecular Formula	C9H13ClNOP
Molecular Weight	217.63 g/mol
Synonyms	Chloro(dimethylamino)(4-methoxyphenyl)phosphine; (4-Methoxyphenyl)chloro(dimethylamino)phosphine; Dimethyl(4-methoxyphenyl)phosphoramidous Chloride; (p-Methoxyphenyl)chloro(dimethylamino)phosphine; N,N-Dimethyl-P-chloro-P-(4-methoxyphenyl)phosphinous amide; 4-Methoxyphenylchloro(dimethylamino)phosphine
EINECS	Contact for details

Quality Control

Our production of 4-Methoxyphenyl(Dimethylamino)Chlorophosphine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizers and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.