Description

Bis(Dimethylamino)Chlorophosphine is a versatile organophosphorus reagent featuring a reactive P-Cl bond and two dimethylamino substituents. This compound is a critical building block in synthetic organic and organometallic chemistry, enabling the efficient introduction of phosphorus-containing functional groups. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphorus heterocycles or phosphoramidate prodrugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where phosphorus-based compounds are central to biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of sophisticated phosphorus-based ligands used in catalysis (e.g., for cross-coupling reactions).
• Polymer Chemistry: Employed as a monomer or modifying agent in the synthesis of flame-retardant polymers and specialty materials with tailored properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and developing novel organophosphorus compounds.
• Electrolyte Additive: Investigated for use in advanced battery systems to improve electrolyte stability and performance.

Basic Information

Product Name	Bis(Dimethylamino)Chlorophosphine
CAS No.	3348-44-5
Molecular Formula	C4H12ClN2P
Molecular Weight	154.58 g/mol
Synonyms	Chlorobis(dimethylamino)phosphine; N,N,N',N'-Tetramethylphosphorodiamidous Chloride; Phosphorodiamidous Chloride, Tetramethyl-; Tetramethylphosphorodiamidous Chloride; Bis(dimethylamino)phosphinous Chloride; (Dimethylamino)phosphonous Dichloride (related); DMAP-Cl; BDMACP
EINECS	222-110-1

Quality Control

Our Bis(Dimethylamino)Chlorophosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (NMR)	≥ 97.0%
Chloride Content	22.5 - 23.5 %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.