Description

(4,5-Dihydro-1-Methyl-4-Oxo-1H-Imidazol-2-Yl)Phosphoramidic Dichloride is a high-purity, reactive organophosphorus intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for creating complex molecules with specific biological or material properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or possessing specific receptor activity.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, insecticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphoramidate ligands used in asymmetric catalysis and metal complexation.
• Peptide Mimetics and Prodrug Design: Employed in the construction of phosphate and phosphoramidate analogs of amino acids and nucleotides for biomedical research.
• Chemical Biology Probes: Utilized to develop activity-based probes and labeling reagents for studying biochemical pathways.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of novel polymers with tailored properties.

Basic Information

Product Name	(4,5-Dihydro-1-Methyl-4-Oxo-1H-Imidazol-2-Yl)Phosphoramidic Dichloride
CAS No.	25221-53-8
Molecular Formula	C₄H₆Cl₂N₃O₂P
Molecular Weight	229.98 g/mol
Synonyms	1-Methyl-4-oxo-4,5-dihydro-1H-imidazole-2-phosphoramidic dichloride; 2-Phosphoramidic dichloride, 4,5-dihydro-1-methyl-4-oxo-1H-imidazole; N-(Dichlorophosphinyl)-1-methyl-2-imidazolidinone-4-one; 1-Methylhydantoin-2-ylphosphoramidic dichloride; Phosphoramidic dichloride, (4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-; Hydantoin phosphoramidochloridate derivative
EINECS	Contact for details

Quality Control

Every batch of (4,5-Dihydro-1-Methyl-4-Oxo-1H-Imidazol-2-Yl)Phosphoramidic Dichloride is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.