Description

Di-(o-Tolyl)Phosphinbromid is a specialized organophosphorus compound primarily used as a key ligand precursor in advanced chemical synthesis. This compound matters for its role in facilitating critical cross-coupling reactions, enabling the production of complex molecules with high precision and efficiency. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for catalyst development.

Application

• Pharmaceutical Intermediate Synthesis: Serves as a crucial precursor for phosphine ligands used in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to construct complex drug molecules.
• Catalyst Development: Employed in the research and production of specialized homogeneous catalysts for fine chemical and polymer manufacturing.
• Agrochemical Research: Used in the synthesis of novel organophosphorus active ingredients and ligands for catalytic processes in crop protection agent development.
• Materials Science: Acts as a building block for creating novel phosphine-based ligands used in OLED materials, conductive polymers, and other advanced functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and organometallic chemistry within university and corporate research laboratories.

Basic Information

Product Name	Di-(o-Tolyl)Phosphinbromid
CAS No.	256440-00-3
Molecular Formula	C14H14BrP
Molecular Weight	293.14 g/mol
Synonyms	Di(2-methylphenyl)phosphinous bromide; Bis(2-methylphenyl)phosphinous bromide; (2-Methylphenyl)phosphonous dichloride, bromo-; o-Tolylphosphonous dichloride, bromo-; Di-o-tolylphosphinous bromide; Phosphinous bromide, bis(2-methylphenyl)-; Di(2-tolyl)phosphinbromid
EINECS	Contact for details

Quality Control

Our Di-(o-Tolyl)Phosphinbromid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 31P), HPLC, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a controlled, dry environment and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	Conforms
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.