Description

2-Deoxyribosyl-8-Azapurine-2-One 5'-Monophosphate is a chemically modified nucleoside monophosphate analog, a key building block in advanced biochemical research and pharmaceutical development. Its primary value lies in its role as a precursor or intermediate in the synthesis of novel nucleotide-based therapeutics, including antiviral and anticancer agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing next-generation targeted therapies and diagnostic tools.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel purine nucleoside analog drugs targeting viral replication and cancer cell proliferation.
• Antiviral Drug Research: Used in the development of nucleotide reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
• Oncology Research: Serves as a building block for creating chemotherapeutic agents that interfere with DNA synthesis in malignant cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate the mechanisms of DNA polymerases and other nucleic acid-processing enzymes.
• Prodrug Development: Utilized in the design of nucleotide prodrugs to enhance cellular uptake and therapeutic efficacy.
• Diagnostic Probe Synthesis: A component in the creation of labeled nucleotides for use in molecular diagnostics and imaging.

Basic Information

Product Name	2-Deoxyribosyl-8-Azapurine-2-One 5'-Monophosphate
CAS No.	79821-52-6
Molecular Formula	C9H12N5O7P
Molecular Weight	333.20 g/mol
Synonyms	8-Aza-2'-deoxyinosine 5'-monophosphate; 8-Azapurine-2-one, 2-deoxyribosyl-, 5'-monophosphate; 8-Aza-dIMP; 2'-Deoxy-8-azainosine 5'-monophosphate; 8-Aza-2'-deoxyinosine monophosphate; 8-Azahypoxanthine 2'-deoxyribonucleotide; 8-Aza-dIno-5'-MP
EINECS	Contact for details

Quality Control

Every batch of 2-Deoxyribosyl-8-Azapurine-2-One 5'-Monophosphate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.