Description

1-(Triethylsilyloxy)-1,3-Butadiene, 97%, Mixture Of Cis And Trans is a high-purity silyl enol ether derivative, a versatile and reactive intermediate in advanced organic synthesis. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in Diels-Alder and other cycloaddition reactions, which are critical for constructing complex molecular architectures. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for constructing cyclic frameworks.
• Diels-Alder Reactions: Serves as a highly reactive diene component in [4+2] cycloadditions to form six-membered rings with precise stereochemical control.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides requiring specific cyclic structures.
• Material Science Research: Employed in the synthesis of novel organic materials and polymers with tailored properties.
• Asymmetric Synthesis: Valuable chiral building block for the preparation of enantiomerically pure compounds in medicinal chemistry.
• Process Chemistry: Utilized in scale-up and optimization of manufacturing routes for high-value fine chemicals.

Basic Information

Product Name	1-(Triethylsilyloxy)-1,3-Butadiene, 97%, Mixture Of Cis And Trans
CAS No.	79746-17-1
Molecular Formula	C10H20OSi
Molecular Weight	184.35 g/mol
Synonyms	1,3-Butadien-1-ol, 1-(triethylsilyl)-, (1E)-; 1-(Triethylsilyloxy)buta-1,3-diene; (E)-1-(Triethylsilyloxy)-1,3-butadiene; Triethyl(1,3-butadien-1-yloxy)silane; 1-Triethylsilyloxy-1,3-butadiene; TES butadiene enol ether; 1,3-Butadiene, 1-(triethylsilyloxy)-; 1-TESO-butadiene
EINECS	Contact for details

Quality Control

Our 1-(Triethylsilyloxy)-1,3-Butadiene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure it meets the specified 97% minimum purity and consistent isomeric ratio. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Isomeric Ratio (cis/trans)	Typical mixture, ratio available on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.