Description

2-(Difluoromethylthio)Benzoyl Chloride is a specialized organosulfur and organofluorine building block, serving as a key reactive intermediate in advanced synthetic chemistry. Its molecular architecture, featuring both a benzoyl chloride and a difluoromethylthio group, makes it a versatile precursor for constructing complex molecules with tailored properties. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated thioether motifs into target compounds.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used as a key building block in the production of advanced pesticides, herbicides, and fungicides, where the difluoromethylthio group can improve efficacy and environmental profile.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require the incorporation of fluorine and sulfur for specific chemical resistance or surface properties.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical companies offering bespoke synthesis services for complex, multi-step organic molecules.

Basic Information

Product Name	2-(Difluoromethylthio)Benzoyl Chloride
CAS No.	79676-60-1
Molecular Formula	C8H5ClF2OS
Molecular Weight	222.64 g/mol
Synonyms	2-[(Difluoromethyl)sulfanyl]benzoyl chloride; Benzoyl chloride, 2-[(difluoromethyl)thio]-; o-(Difluoromethylthio)benzoyl chloride; 2-(Difluoromethylmercapto)benzoyl chloride; 2-(Difluoromethylsulfanyl)benzoyl chloride; α,α-Difluoro-o-(mercaptomethyl)benzoyl chloride (related); DFMT-Benzoyl Chloride
EINECS	Contact for details

Quality Control

Our production of 2-(Difluoromethylthio)Benzoyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.