Description

6-Azido-Hexanoic Acid is a versatile bifunctional organic compound featuring both a carboxylic acid and a reactive azide group, making it a critical building block for click chemistry and bioconjugation. This compound is essential for researchers and manufacturers who require a reliable linker to create stable covalent bonds between molecules under mild, aqueous conditions. It is particularly valuable for professionals in pharmaceutical development, materials science, and proteomics who are developing targeted drug delivery systems, functional polymers, or diagnostic assays.

Application

• Bioconjugation & Click Chemistry: Serves as a key linker for attaching fluorescent dyes, peptides, or drugs to antibodies, proteins, and nanoparticles via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, enabling the creation of targeted therapeutics with improved pharmacokinetic properties.
• Polymer & Materials Science: Functionalizes polymer backbones and surfaces to introduce azide handles for further modification, creating smart hydrogels, coatings, and advanced functional materials.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and chemical proteomics to label and study enzyme activity and protein function within complex biological systems.
• Diagnostic Reagent Synthesis: A precursor for manufacturing contrast agents, imaging probes, and components for diagnostic kits that require specific molecular tagging.
• Cross-linking Agent: Acts as a homobifunctional cross-linker to conjugate biomolecules or synthetic polymers, forming stable triazole linkages.

Basic Information

Product Name	6-Azido-Hexanoic Acid
CAS No.	79598-53-1
Molecular Formula	C6H11N3O2
Molecular Weight	157.17 g/mol
Synonyms	6-Azidohexanoic Acid; 5-Azidopentane-1-carboxylic Acid; Azidohexanoic Acid; Hexanoic acid, 6-azido-; ω-Azidohexanoic Acid; 6-Azidocaproic Acid; N3(CH2)5COOH
EINECS	Contact for details

Quality Control

Our 6-Azido-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may lead to decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.