Description

2,4,6-Trifluorobenzoyl Chloride is a highly reactive and versatile fluorinated aromatic acid chloride. This compound serves as a critical building block for introducing the 2,4,6-trifluorobenzoyl moiety into more complex molecular architectures, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where precise fluorination patterns are required to modulate biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethylbenzoyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving thermal stability and optical properties.
• Polymer Modification: Employed to introduce fluorine atoms into polymer backbones or side chains, enhancing chemical resistance and lowering surface energy for coatings.
• Organic Synthesis Reagent: A valuable reagent for Friedel-Crafts acylation and nucleophilic substitution reactions in complex organic synthesis.
• Dye & Pigment Manufacturing: Intermediate for creating fluorinated dyes and pigments with improved lightfastness and color properties.

Basic Information

Product Name	2,4,6-Trifluorobenzoyl Chloride
CAS No.	79538-29-7
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,4,6-Trifluorobenzoyl chloride; Benzoyl chloride, 2,4,6-trifluoro-; α,α,α-Trifluoroisophthaloyl chloride (unsymmetrical); 2,4,6-Trifluorobenzoic acid chloride; Isophthaloyl chloride, 2,4,6-trifluoro-; TFBC
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and ensure maximum shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.