Description

(2,6-Difluoro-4-Methoxyphenyl)Methanol is a high-value fluorinated aromatic building block characterized by its difluorinated methoxyphenyl core and a reactive benzylic alcohol group. This compound matters as a critical intermediate for synthesizing advanced agrochemicals and pharmaceuticals, where its fluorine atoms and functional handle enable precise tuning of biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging fluorine's ability to enhance metabolic stability and membrane permeability.
• Pharmaceutical Building Block: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and oncology, where the difluoromethoxy moiety is advantageous.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated aromatic components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart improved chemical resistance, thermal stability, and lower dielectric constants.
• Cross-Coupling Reagent: The benzylic alcohol can be functionalized to create partners for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Ligand & Catalyst Synthesis: Utilized in the preparation of sophisticated chiral and non-chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(2,6-Difluoro-4-Methoxyphenyl)Methanol
CAS No.	79538-27-5
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	2,6-Difluoro-4-methoxybenzyl alcohol; (2,6-Difluoro-4-methoxyphenyl)methanol; 4-Methoxy-2,6-difluorobenzyl alcohol; 2,6-Difluoro-4-methoxybenzenemethanol; 2,6-Difluoro-p-anisyl alcohol; 2,6-Difluoro-4-methoxybenzylalcohol; α-Hydroxy-2,6-difluoro-4-methoxytoluene
EINECS	Contact for details

Quality Control

Our (2,6-Difluoro-4-Methoxyphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.