Description

2,3,5,6-Tetrafluoro-4-Methylbenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its value lies in the unique combination of the reactive benzyl alcohol group and the electron-withdrawing, lipophilicity-enhancing tetrafluoro substitution pattern. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Employed to introduce fluorinated benzyl groups into polymers, altering surface properties, chemical resistance, and thermal stability.
• Organic Electronics: Acts as a building block for electron-transport materials and other components in OLEDs and organic photovoltaics.
• Cross-Coupling Reactions: The benzyl alcohol can be functionalized or the ring can participate in metal-catalyzed coupling reactions to create diverse biaryl structures.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Methylbenzyl Alcohol
CAS No.	79538-03-7
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	α,2,3,5,6-Pentafluoro-p-tolylmethanol; (2,3,5,6-Tetrafluoro-4-methylphenyl)methanol; 4-(Hydroxymethyl)-2,3,5,6-tetrafluorotoluene; 2,3,5,6-Tetrafluoro-4-methylbenzenemethanol; Pentafluoro-4-methylbenzyl Alcohol; 79538-03-7; 2,3,5,6-Tetrafluoro-4-methyl-benzyl alcohol
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoro-4-Methylbenzyl Alcohol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of a desiccant or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.