Description

2-Chloro-6-Fluorobenzene-1-Carbonyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-chloro-6-fluorobenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing a fluorinated benzoyl group.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity.
• Ligand and Material Science: Building block for creating specialized ligands for catalysis and advanced polymers or liquid crystals.
• Custom Synthesis and R&D: Employed in research laboratories for method development and the creation of novel chemical entities for screening.
• Dyestuff and Pigment Intermediate: Can be utilized in the synthesis of complex dyes and organic pigments.

Basic Information

Product Name	2-Chloro-6-Fluorobenzene-1-Carbonyl Chloride
CAS No.	79455-63-3
Molecular Formula	C7H3Cl2FO
Molecular Weight	192.99 g/mol
Synonyms	2-Chloro-6-fluorobenzoyl chloride; 2-Chloro-6-fluorobenzoic acid chloride; 6-Fluoro-2-chlorobenzoyl chloride; 2-Chloro-6-fluorobenzenecarbonyl chloride; 2-Chloro-α,α-difluorotoluene (misleading, but sometimes indexed); Benzoic acid, 2-chloro-6-fluoro-, chloride; 79455-63-3 (CAS)
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-6-Fluorobenzene-1-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.