Description

Triiodothyronine, Reverse Sulfate is a chemically modified thyroid hormone analog, specifically the reverse T3 sulfate conjugate. This compound is of significant interest in biochemical and pharmaceutical research for studying thyroid hormone metabolism, transport, and receptor interactions. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector, particularly those focused on endocrinology, diagnostic assay development, and novel therapeutic pathways.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and research.
• Biochemical Research: Essential for in-vitro studies investigating the sulfation pathway of thyroid hormones and its role in hormone regulation and deactivation.
• Diagnostic Development: Acts as a key antigen or standard in the development and validation of immunoassays for thyroid function testing.
• Metabolite Studies: Utilized in metabolic profiling and pharmacokinetic research to understand the fate of thyroid hormone analogs.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in endocrinology and cell signaling.

Basic Information

Product Name	Triiodothyronine, Reverse Sulfate
CAS No.	79349-15-8
Molecular Formula	C15H12I3NO7S
Molecular Weight	788.93 g/mol
Synonyms	Reverse T3 Sulfate; 3,3',5'-Triiodothyronine Sulfate; rT3S; 3,3',5'-Triiodo-L-thyronine Sulfate; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid sulfate; L-Reverse Triiodothyronine Sulfate; 3,3',5'-Triiodothyronine O-Sulfate
EINECS	Contact for details

Quality Control

Our Triiodothyronine, Reverse Sulfate is manufactured and controlled under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents and moisture content. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.