Description

2-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci) is a versatile and reactive heterocyclic building block, primarily valued for its role as an acylating agent in organic synthesis. Its core value proposition lies in enabling the efficient introduction of the 4-methylthiazole-2-carbonyl moiety, a key structural motif in advanced chemical development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiazole heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the thiazole ring can contribute to efficacy.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, or organic electronic materials that require specific heterocyclic components.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for labeling or modifying biomolecules in probe development and biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & R&D Laboratories: Employed in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci)
CAS No.	79312-42-8
Molecular Formula	C5H4ClNOS
Molecular Weight	161.61 g/mol
Synonyms	4-Methyl-1,3-thiazole-2-carbonyl chloride; 4-Methylthiazole-2-carbonyl chloride; 2-Carbonyl chloride-4-methylthiazole; 4-Methyl-2-thiazolecarbonyl chloride; 4-Methylthiazole-2-carboxylic acid chloride; 4-Methyl-1,3-thiazole-2-carboxylic acid chloride; 4-Methyl-2-thiazolylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.