Description

2,4,16A-Tribromoestrone is a brominated derivative of the natural estrogen estrone, serving as a key synthetic intermediate and reference standard in advanced chemical research and development. This compound is valued for its specific molecular modifications, which are critical for studying structure-activity relationships and developing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on steroid chemistry and endocrine system research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthetic pathway for novel steroid-based therapeutics and research compounds.
• Biochemical Research: Used as a reference standard and probe in studies investigating estrogen receptor binding, metabolism, and hormonal activity.
• Academic & R&D Laboratories: Serves as a specialized reagent for method development, organic synthesis projects, and structure elucidation in steroid chemistry.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, brominated steroid derivatives for various experimental applications.
• Metabolite Studies: Useful as a model compound for researching the metabolic pathways and environmental fate of halogenated steroids.

Basic Information

Product Name	2,4,16A-Tribromoestrone
CAS No.	79258-15-4
Molecular Formula	C₁₈H₂₁Br₃O₂
Molecular Weight	525.07 g/mol
Synonyms	2,4,16α-Tribromoestrone; 2,4,16α-Tribromo-3-hydroxyestra-1,3,5(10)-trien-17-one; Estrone, 2,4,16α-tribromo-; 2,4,16α-Tribromo-oestra-1,3,5(10)-trien-3-ol-17-one
EINECS	Contact for details

Quality Control

Our 2,4,16A-Tribromoestrone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure identity, strength, and composition. We provide full traceability and Certificates of Analysis (COA) are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.